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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECH1
All Species:
8.79
Human Site:
S57
Identified Species:
21.48
UniProt:
Q13011
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13011
NP_001389.2
328
35816
S57
A
P
D
H
S
Y
E
S
L
R
V
T
S
A
Q
Chimpanzee
Pan troglodytes
XP_001167817
328
35675
S57
A
P
D
H
S
Y
E
S
L
R
V
T
S
A
Q
Rhesus Macaque
Macaca mulatta
XP_001084167
320
35031
K57
L
R
V
T
S
A
Q
K
H
V
L
H
V
Q
L
Dog
Lupus familis
XP_533678
328
35870
S57
A
P
G
H
S
Y
E
S
L
R
V
T
A
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35459
327
36100
I57
S
D
H
N
Y
E
S
I
Q
V
T
S
A
Q
K
Rat
Rattus norvegicus
Q62651
327
36153
I57
S
D
H
N
Y
E
S
I
Q
V
T
S
A
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086341
285
31456
A57
F
Q
A
I
S
E
D
A
S
C
R
A
V
V
I
Zebra Danio
Brachydanio rerio
NP_001006068
308
33755
K57
V
E
I
S
R
P
E
K
R
N
A
M
N
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608375
312
33800
L57
P
F
V
F
H
V
E
L
H
R
P
S
K
F
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784041
285
31394
D57
N
T
I
A
T
D
E
D
C
R
V
V
L
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
92.9
79.8
N.A.
74
75.3
N.A.
N.A.
N.A.
62.2
62.5
N.A.
48.1
N.A.
N.A.
51.2
Protein Similarity:
100
99.3
95.7
88.7
N.A.
87.8
87.8
N.A.
N.A.
N.A.
73.1
75
N.A.
65.5
N.A.
N.A.
65.8
P-Site Identity:
100
100
6.6
86.6
N.A.
0
0
N.A.
N.A.
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
20
93.3
N.A.
33.3
33.3
N.A.
N.A.
N.A.
20
13.3
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
10
10
0
10
0
10
0
0
10
10
30
30
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
0
20
20
0
0
10
10
10
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
30
60
0
0
0
0
0
0
0
0
% E
% Phe:
10
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
20
30
10
0
0
0
20
0
0
10
0
0
0
% H
% Ile:
0
0
20
10
0
0
0
20
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
20
0
0
0
0
10
10
20
% K
% Leu:
10
0
0
0
0
0
0
10
30
0
10
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
20
0
0
0
0
0
10
0
0
10
0
10
% N
% Pro:
10
30
0
0
0
10
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
20
0
0
0
0
30
30
% Q
% Arg:
0
10
0
0
10
0
0
0
10
50
10
0
0
0
0
% R
% Ser:
20
0
0
10
50
0
20
30
10
0
0
30
20
0
0
% S
% Thr:
0
10
0
10
10
0
0
0
0
0
20
30
0
0
10
% T
% Val:
10
0
20
0
0
10
0
0
0
30
40
10
20
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
20
30
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _